Vitamin D is involved in a wide variety of metabolic processes, including calcium homeostasis, immune modulation, hormone secretion, cell proliferation and dif- ferentiation. Hypovitaminosis D has been increasingly recognized as an inde- pendent risk factor for cardiovascular and related diseases.
Chemotherapy and radiation are basic cancer therapies aimed at reducing tumor burden. These toxic agents destroy both malignant and normal cells thereby increasing the population of dying cells and/or tumor debris and causing other changes in the tumor microenvironment. These dead cells can act as a source of stimulants on surviving tumor cells
In recent years, many studies have shown positive effects of vitamin D on health, including various benefits to inflammation and immune response, cognitive function, protection against metabolic syndrome and cardiovascular disease.1 Vitamin D deficiency has been closely related to the development of coronary heart disease and its mortality.
Colorectal cancer is the second most deadly cancer in the United States and there is an urgent need to develop effective preventive and therapeutic strategies against it. The aim of our study was to investigate the antitumor effects of a nutrient mixture containing ascorbic acid, lysine, proline and green tea extract that has been previously demonstrated a strong anticancer activity in several cancer cell types.
Bone is a specialized connective tissue and its formation involves many steps and stages. It is a dynamic tissue that responds to many internal and external factors and adapts to changing functional conditions. Bone is composed of various types of cells and collagenous extracellular organic matrix, which is predominantly type I collagen (85–95%) that becomes hardened by the deposition of [...]